Suicide gene - Wikipedia
A suicide gene, in genetics, will cause a cell to kill itself through apoptosis. Activation of these genes can be due to many processes, but the main cellular "switch" to induce apoptosis is the p53 protein.
Gene that raises suicide risk identified | Science | The ...
The gene appears to be more common in depressed people who have attempted suicide than in those who have not
A Suicide Gene - Genome News Network - Home
A Suicide Gene: Is there a genetic cause for suicide? By Sharon Guynup. May 12, 2000. The pattern seems so familiar: a business reversal, the breakup of a marriage, school failure, depression, a downward spiral leading eventually to suicide. The apparent links between failure, depression and suicide have become a cultural icon, appearing over ...
Suicide Gene - an overview | ScienceDirect Topics
Mukesh Kumar, Ambikanandan Misra, in Challenges in Delivery of Therapeutic Genomics and Proteomics,. 2011. 220.127.116.11 Suicide Gene Therapy. Suicide gene therapy, also known as gene-directed enzyme prodrug therapy (GDEPT), is the most commonly used approach for solid tumors. The suicide genes, when transduced into target cells, convert inactive prodrugs into cytotoxic metabolites for the host cells.
Suicide Gene Therapy For Treatment: How it Works
In suicide gene therapy, doctors may modify a virus or bacterium, such as E. coli, to safely deliver a cancer-killing gene to mesothelioma cells. Genetically modifies cancer cells with “suicide gene” Prodrug, which is a type of chemotherapy, then causes modified cancer cells to self-destruct ...
Suicide Gene Therapy for Cancer – Current Strategies
Suicide gene therapy is a therapeutic strategy, in which cell suicide inducing transgenes are introduced into cancer cells. The two major suicide gene therapeutic strategies currently pursued are: cytosine deaminase/5-fluorocytosine and the herpes simplex virus/ganciclovir. The novel strategies include silencing gene expression, expression of ...
Is There a Suicide Gene? - The Daily Beast
Is There a Suicide Gene? Depression and bipolar disorder may be in your DNA—but is suicide? Several high-profile families have been plagued by the phenomena.
Definition of Suicide gene - MedicineNet
Suicide gene: A gene whose expression in a cell is lethal for that cell. Suicide genes form the basis of a strategy for making cancer cells more vulnerable, more sensitive to chemotherapy.The approach has been to attach parts of genes expressed in cancer cells to other genes for enzymes not found in mammals that can convert a harmless substance into one that is toxic to the tumor.
Suicide Gene Identified | The Scientist Magazine®
The fact that suicide can run in families, as well as more direct studies of heritability involving twins or adopted individuals, has suggested a genetic component to suicidal behavior, but what genes are involved has remained unclear. Now, researchers have identified a gene variant that is more ...
Genetic link to suicidal behavior confirmed -- ScienceDaily
A new study has found evidence that a specific gene is linked to suicidal behavior, adding to our knowledge of the many complex causes of suicide. This research may help doctors one day target the ...