Oncogene - Wikipedia
An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated or expressed at high levels.. Most normal cells will undergo a programmed form of rapid cell death when critical functions are altered and malfunctioning.Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead.
GPR55 signalling promotes proliferation of pancreatic ...
The life expectancy for pancreatic cancer patients has seen no substantial changes in the last 40 years as very few and mostly just palliative treatments are available.
RET proto-oncogene - Wikipedia
The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular signalling molecules. RET loss of function mutations are associated with the development of Hirschsprung's disease,  while gain of function mutations are associated with the development of various types of human cancer ...
Cell cycle plasticity driven by MTOR signaling: integral ...
Pancreatic ductal adenocarcinoma (PDAC), like many KRAS-driven tumors, preferentially loses CDKN2A that encodes an endogenous CDK4/6 inhibitor to bypass the RB-mediated cell cycle suppression.
Oncogene Impact IF 2018|2017|2016 - BioxBio
Oncogene Impact Factor, IF, number of article, detailed information and journal factor. ISSN: 0950-9232.
Rediscovering Biology - Animation Archive
How a Proto-oncogene Becomes an Oncogene: A depiction of some types of mutations that can occur to turn a proto-oncogene into an oncogene. Related Links
Oncogene - Wikipedia
Un oncogene è un gene, o una serie di nucleotidi che codificano una proteina, che potenzialmente indirizzano la cellula verso lo sviluppo di un fenotipo neoplastico.Solitamente gli oncogeni intervengono nello sviluppo tumorale e aumentano le possibilità che lo sviluppo (proliferazione e differenziamento) di una cellula si diriga in senso tumorale.
INTRODUCTION — A group of patients with non-small cell lung cancer (NSCLC) have tumors that contain an inversion in chromosome 2 that juxtaposes the 5' end of the echinoderm microtubule-associated protein-like 4 (EML4) gene with the 3' end of the anaplastic lymphoma kinase (ALK) gene, resulting in the novel fusion oncogene EML4-ALK .This fusion oncogene rearrangement is transforming both ...
Oncogenes and tumor suppressor genes | American Cancer Society
Proto-oncogenes are genes that normally help cells grow. When a proto-oncogene mutates (changes) or there are too many copies of it, it becomes a "bad" gene that can become permanently turned on or activated when it is not supposed to be. When this happens, the cell grows out of control, which can ...