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Human Genome Overview - Genome Reference Consortium
Next assembly update The GRC will review data for the next assembly update in summer 2019. The GRC remains committed to its mission to improve the human reference genome assembly, correcting errors and adding sequence to ensure it provides the best representation of the human genome to meet basic and clinical research needs.

Human Genome Reference Program | NHGRI
The human genome reference, currently provided by the Genome Reference Consortium (GRC), is used by essentially all researchers who need to align and assemble experimental or patient genome sequence data.It also serves as a consensus coordinate system for reporting results.

Genome Reference Consortium
The Genome Reference Consortium. Putting sequences into a chromosome context. The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome.

Reference Genome - an overview | ScienceDirect Topics
University of Santa Cruz (UCSC) that also hosts the central repository for ENCODE data (Raney et al., 2011) and the Genome Reference Consortium (GRC) that creates reference assemblies (The Genome Reference Consortium). hg18 and hg19 are the two versions of the human genome offered by UCSC while GRCh36 and GRCh37 are the two versions offered by GRC.

Human genome reference builds - GRCh38 or hg38 - b37 ...
1. Background. Successive "versions" of the human genome reference, commonly called assemblies or builds, have been published since the original draft Human Genome Project publication, bringing gradual improvements in quality made possible by technological advances, as well as improvements in the representativeness of the reference genome sequence with regard to historically underrepresented ...

Reference genome – GATK
This document covers the general motivation behind the use of genome references, as well as some terminology and related considerations. For more specific information about human genome reference assemblies, please see the Dictionary entry on Human genome reference builds.For help dealing with reference compatibility problems, see this Troubleshooting doc.

Genome Reference Consortium | Wellcome Sanger Institute
The Genome Reference Consortium was founded in 2007 to improve the reference genome assemblies of human, mouse and zebrafish.One of the first tasks was to modernise the assembly model to make sure that complex variation within a species can be captured and represented. The GRC also guarantees INSDC submission and long term maintenance of all produced assemblies.

Reference genome - Wikipedia
The human reference genome GRCh38 was released from the Genome Reference Consortium on 17 December 2013. The previous human reference genome (GRCh37) was the nineteenth version. This build contained around 250 gaps, whereas the first version had roughly 150,000 gaps. The GRCh38 assembly saw the closure or reduction of more than 100 gaps.

Get to Know Your Reference Genome (GRCh37 vs GRCh38 ...
Both, GRCh37 and GRCh38 are human genome assemblies by the Genome Reference Consortium (GRC). GRCh38 (also called “build 38”) was released four years after the GRCh37 release in 2009, so it can be viewed as a version with updated annotations to the earlier assembly.

Genetics Home Reference - NIH
Genetics Home Reference provides consumer-friendly information about the effects of genetic variation on human health. Health Conditions. Learn about the signs and symptoms, causes, and inheritance of more than 1,300 health conditions with a genetic basis. Browse A–Z. Genes.

 

 

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