The Genome Reference Consortium - National Center for Biotechnology ...
The Genome Reference Consortium. Putting sequences into a chromosome context. The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome.
RefSeq: NCBI Reference Sequence Database - National Center for ...
A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
Human Genome Overview - Genome Reference Consortium
The GRC remains committed to its mission to improve the human reference genome assembly, correcting errors and adding sequence to ensure it provides the best representation of the human genome to meet basic and clinical research needs.
RefSeq curation and annotation of the human reference genome
The human reference genome sequence is an essential resource for clinical, forensic, and research uses. Accurate annotation of known genes, and prediction of novel genes based on available transcript evidence, provides indespensable functional context that supports use of this sequence resource.
Frequently Asked Questions - Genome Reference Consortium
The human reference genome is a composite genome, derived from the sequence of several different anonymous individuals. Approximately 93% of the GRCh38 primary assembly (the assembled chromosomes, unlocalized and unplaced sequences) consists of sequences from 11 genomic clone libraries (a library can generally be considered a proxy for an ...
A complete reference genome improves analysis of human genetic ...
Relative to the current human reference genome, GRCh38, the Telomere-to-Telomere CHM13 (T2T-CHM13) genome closes all remaining gaps, adds nearly 200 million base pairs (Mbp) of sequence, corrects thousands of structural errors, and unlocks the most complex regions of the human genome for scientific inquiry.
Genomes - NCBI - National Center for Biotechnology Information
NCBI's Genome resources include information on large-scale genomics projects, genome sequences and assemblies, and mapped annotations, such as variations, markers and data from epigenomics studies. How to. Submit sequence data to NCBI; Download a complete genome; Convert feature coordinates between genomic assemblies
GRCh37 - hg19 - Genome - Assembly - NCBI
Homo sapiens (human) genome assembly GRCh37 (hg19) from Genome Reference Consortium [GCA_000001405.1 GCF_000001405.13]
Genome Assemblies - Genome Reference Consortium - National Center for ...
The GRC has built tools to facilitate the curation of genome assemblies based on the sequence overlaps of long, high quality sequences (clones and PCR products, not short sequence reads). The GRC currently supports production of assemblies for human, mouse or zebrafish.
Understanding the New Genome Assemblies - NCBI Insights
In response to this, modern genomic data sets present a model of the genome known as a genome assembly. This post will introduce the basic concepts of how we produce such assemblies as well as some basic vocabulary.
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